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A compound in horse chestnut extract has been found to improve sperm quality and decrease varicocele in men with varicocele-associated infertility.

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Horse chestnut seed extract may reduce inflammation related to chronic venous insufficiency, trauma, surgery, or injuries.

A 2-month study in over 100 men with varicocele-associated infertility found that taking 30 mg of aescin every 12 hours improved sperm density, sperm motility, and sperm quality.

In most studies, the dosage used is 100—150 mg of aescin per day.

Reported side effects of horse chestnut seed extract are mild and include digestion issues, upset stomach, dizziness, , and itching.

edema, or swelling of the legs• Files are available under licenses specified on their description page.